tag:blogger.com,1999:blog-4123559132014627431.post7862641709870853743..comments2024-03-29T04:00:27.058-07:00Comments on Eurogenes Blog: Recent gene flow from Africa and the Near East into EuropeDavidskihttp://www.blogger.com/profile/04637918905430604850noreply@blogger.comBlogger15125tag:blogger.com,1999:blog-4123559132014627431.post-37738737654803006222013-07-09T03:28:06.539-07:002013-07-09T03:28:06.539-07:00I know, that's why I said not the majority of ...I know, that's why I said not the majority of it. Overall MENA admix in the RFMix table is not that different between Southern and Northern Europe, and since Neolithic farmer ancestry is already higher in the south, there can't be more than a small amount that's recent. Also as you said there's no mention of any dates. A little of it might be from empires and the slave trade, but Vincenthttps://www.blogger.com/profile/08663869722105662445noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-25501368728370583612013-07-08T19:26:43.550-07:002013-07-08T19:26:43.550-07:00Well, we now know that even Northern Europeans car...Well, we now know that even Northern Europeans carry significant levels of Neolithic farmer ancestry, which probably arrived in Europe from Anatolia and surrounds. And yet there's obviously a huge difference between the potentially Near Eastern and North African IBD levels in Northern and Southern Europe. So there's definitely been gene flow from the Near East and North Africa into EuropeDavidskihttps://www.blogger.com/profile/04637918905430604850noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-74158103071975658372013-07-08T02:29:00.551-07:002013-07-08T02:29:00.551-07:00Recent? Doubtful. At least not the majority of it....Recent? Doubtful. At least not the majority of it.<br /><br /><a href="http://i44.tinypic.com/2v806li.png" rel="nofollow">http://i44.tinypic.com/2v806li.png</a>Vincenthttps://www.blogger.com/profile/08663869722105662445noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-31112073288188866392013-06-05T03:48:34.490-07:002013-06-05T03:48:34.490-07:00True, but that need not mean the direction of gene...True, but that need not mean the direction of gene flow was from Jews to gentiles, at least not in all cases. It might actually be the result of the ancestors of these gentiles acting as donors to the Ashkenazi Jewish population at its formative stage, before it experienced strong founder effect and genetic drift.<br /><br />See, once a population goes through a bottleneck and drift it creates Davidskihttps://www.blogger.com/profile/04637918905430604850noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-87385149194285784212013-06-05T03:30:58.812-07:002013-06-05T03:30:58.812-07:00On the paucity of Jewish ancestry: the Eurogenes A...On the paucity of Jewish ancestry: the Eurogenes Ashkenazi ancestry test found more than 1% among Southern & Central Europeans, and the Ashkenazi label itself is only a quarter to a third of the “Jewish genome.”Sgt. Gilhttps://www.blogger.com/profile/16093774878169751410noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-9547645731249624822013-06-04T07:00:15.786-07:002013-06-04T07:00:15.786-07:00"This study can be criticized for a lack of s..."This study can be criticized for a lack of samples, and using low samples from many regions, but surely we're used to that by now?"<br /><br />Right. 19 from Algeria doesn't begin to cut it; the genetic diversity in Algeria alone would surprise most people, and a detailed study of Maghreb Y-SNPs and aDNA is sorely needed (There are certain hot spots of R1b for example) Their Mark Dhttps://www.blogger.com/profile/03792117663748801194noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-75419840798936092332013-06-04T01:01:24.628-07:002013-06-04T01:01:24.628-07:00Ah, so the European component in Morocco relates t...Ah, so the European component in Morocco relates to more ancient stuff (rather than more recent Vandals and Romans or what have you), so doesn't have much an IBD signal within the frame they are examining. That's an interesting explanation.<br /><br />Populations in North Africa must have been quite structured for some time for this to have been ancient but not to have leaked out much Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-21146679957905931352013-06-03T22:03:28.045-07:002013-06-03T22:03:28.045-07:00The threshold for the IBD detection was set at >...The threshold for the IBD detection was set at >1.5cM. Such segments are unlikely to be older than 5,000 years, apart from a minority of false positives.<br /><br />Also, it's not just the cM that tells us this, but the fact that this haplotype sharing between Europe and North Africa and the Near East creates significant substructures within the European sample. If it was the result of Davidskihttps://www.blogger.com/profile/04637918905430604850noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-3528895440872424932013-06-03T21:15:31.077-07:002013-06-03T21:15:31.077-07:00It's a bit confusing because, on one side, as ...It's a bit confusing because, on one side, as you say, there is no clear time estimate for the IBD data, so it could be your own of 5000 years but it could also be anything else. How can we know if at all? On the other side the term "Near Eastern" here seems to mean more Egypt and Arabia (Qatar) than what we usually understand by Near East (Turkey, the Levant, Iraq, Iran...), so we Majuhttps://www.blogger.com/profile/12369840391933337204noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-21913534567997932862013-06-03T15:05:41.837-07:002013-06-03T15:05:41.837-07:00Moroccans and Algerians do have European ancestry,...Moroccans and Algerians do have European ancestry, but most of it is probably older than 4,000 years, so it won't show up in an IBD analysis with a threshold of 1.5cM. But it does show up clearly in the ADMIXTURE analysis.<br /><br />By the way, I've added a PCA based on the IBD data from the supplementary PDF to further underline the likely direction of gene flows.Davidskihttps://www.blogger.com/profile/04637918905430604850noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-12570208851057907492013-06-03T14:57:53.431-07:002013-06-03T14:57:53.431-07:00As for the Cypriot-Lebanese comparison, the Lebane...As for the Cypriot-Lebanese comparison, the Lebanese, even excluding the Muslim ones, carry more southern West Asian and more African genetic influence than Cypriots. Also the elevated Aegean genetic influence in Cypriots shows up there again.Onur Dincerhttps://www.blogger.com/profile/05041378853428912894noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-56967016562604994452013-06-03T14:43:04.520-07:002013-06-03T14:43:04.520-07:00Genetic analyses show that Cypriots have more sout...Genetic analyses show that Cypriots have more southern West Asian and more African genetic influence than Anatolian Greeks, Turks, Armenians and Assyrians. But Cypriots also have an Aegean genetic influence that is elevated by West Asian standards. In short, Cypriots, as is common for island populations, have a peculiar genetic profile and are not a good proxy for any part of West Asia other thanOnur Dincerhttps://www.blogger.com/profile/05041378853428912894noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-5023655827580650722013-06-03T14:37:35.651-07:002013-06-03T14:37:35.651-07:00But as Botigué et al. point out, the North African...<i>But as Botigué et al. point out, the North African samples which show the highest IBD sharing with Iberians are also those with the lowest European ancestry proportions in the ADMIXTURE analysis (see below). Therefore, it's unlikely that this shared IBD is of European origin in any significant degree.</i><br /><br />Presumably, the North African populations with the putatively European Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-59730784267610507282013-06-03T13:02:22.384-07:002013-06-03T13:02:22.384-07:00Cypriots are very similar to nearby populations in...Cypriots are very similar to nearby populations in Lebanon and Turkey, except they lack the recent East Eurasian admixture seen in Turkey. <br /><br />I'd say the levels of Near Eastern, North African and Sub-Saharan IBD across the East Mediterranean would be very similar to those in Cyprus. I'm sure we'll see such data very soon.Davidskihttps://www.blogger.com/profile/04637918905430604850noreply@blogger.comtag:blogger.com,1999:blog-4123559132014627431.post-68314866028229917522013-06-03T12:54:34.679-07:002013-06-03T12:54:34.679-07:00The IBD maps are erroneous, as northern West Asia ...The IBD maps are erroneous, as northern West Asia (Cypriots are a peculiar island population), the Caucasus and the Pontic steppe region are not represented.Onur Dincerhttps://www.blogger.com/profile/05041378853428912894noreply@blogger.com